Non-absorbable sutures are made of non-biodegradable material, so they can not be digested by enzymes or hydrolyzed in tissues. Ultimately, the fibroblasts encapsulate them permanently, so they maintain their maximum resistance over time, except in the case of removal of the postsurgical points. (Skin suture) There are different types of non-absorbable sutures with different levels of resistance, which can be monofilar or multifilar, which will be selected depending on the tissues to be sutured or at the discretion of the professional.